Personally, I can't stand the art style. Chibi (which I didn't know it had a name other than just "anime") is a VERY large part of it for me, but a lot of the animation style just doesn't appeal to me. Oddly, while I couldn't make it through Cowboy Bebop or Fullmetal Alchemist, both Avatar the Last Airbender and Samurai Jack (not technically anime but definitely very heavily influenced by anime) are shows I enjoy, and, as has been mentioned, something done similarly to Avatar for the Iron Kingdoms could be very cool (especially if you do less of the kiddy episodes). I think it would be best done by a young person in possibly Llael discovering their a Warcaster, and then traveling around the various nations trying to learn, focusing on a different nation each season, with Cryx revealing themselves as the bigger threat than Khador later on, causing the warcasters to go to the Nightmare Kingdoms in the final season. But this would also focus almost exclusively on Eastern Immoren and not involve Hordes as much.
As far as other cartoons I really enjoyed, Justice League Unlimited, if they've either gotten better at mixing CGI/human animation or just don't use the CGI parts, was a show I both enjoyed the art style and maturity of.